Conceptualizing neuropsychiatric diseases with multimodal data-driven meta-analyses – The case of behavioral variant frontotemporal dementia
نویسندگان
چکیده
منابع مشابه
Conceptualizing neuropsychiatric diseases with multimodal data-driven meta-analyses - the case of behavioral variant frontotemporal dementia.
INTRODUCTION Uniform coordinate systems in neuroimaging research have enabled comprehensive systematic and quantitative meta-analyses. Such approaches are particularly relevant for neuropsychiatric diseases, the understanding of their symptoms, prediction and treatment. Behavioral variant frontotemporal dementia (bvFTD), a common neurodegenerative syndrome, is characterized by deep alterations ...
متن کاملBehavioral-variant frontotemporal dementia
OBJECTIVE To identify distinct behavioral phenotypes of behavioral-variant frontotemporal dementia (bvFTD) and to elucidate differences in functional, neuroimaging, and progression to residential care placement. METHODS Eighty-eight patients with bvFTD were included in a cluster analysis applying levels of disinhibition and apathy (Cambridge Behavioural Inventory-Revised) to identify phenotyp...
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INTRODUCTION. Behavioural variant frontotemporal dementia is a clinically and pathologically heterogeneous neurodegenerative disorder, characterised by progressive behavioural changes and executive function impairment. It is the second most common neurodegenerative cause of dementia after Alzheimer's type dementia. Atypical course of the disease, including cases with other symptoms relevantly i...
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BACKGROUND Behavioral variant frontotemporal dementia (bvFTD) is pathologically heterogeneous. With emerging therapeutics, determining underlying pathology during life is increasingly important. Neuropsychiatric symptoms are prevalent and diagnostic in bvFTD. METHODS We assessed the neuropsychiatric profile of patients with clinically diagnosed bvFTD as a function of pathology at autopsy. Pat...
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Neurodegenerative dementias that occur in adults can present with significant behavioral symptoms in addition to the cognitive syndrome. These can be disruptive for the families who take care for these patients and cause a significant burden on the medical system. The incidence of Alzheimer’s disease (AD) is frequently greater in patients over 65 years of age, whereas the behavioral variant of ...
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ژورنال
عنوان ژورنال: Cortex
سال: 2014
ISSN: 0010-9452
DOI: 10.1016/j.cortex.2014.02.022